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. 2018 Jul 5;16(3):3545–3554. doi: 10.3892/ol.2018.9085

Figure 6.

Figure 6.

Accumulation of proteins associated with the mitochondria-caspase pathway for apoptosis in response to homoisoflavanone-1 treatment. (A) A549 cells were treated with 0, 12.5, 25, 50 and 100 µg/ml of homoisoflavanone-1 for 24 and analyzed by western blotting. Immunoblotting detected the protein expression of (B) caspase 3, (C) active caspase 3, (D) PARP, (E) Bcl-2 and (F) Bak. β-actin was the loading control. Data are presented as the mean ± standard deviation from three independent experiments. *P<0.05 and **P<0.01 vs. the control group. PARP, poly ADP-ribose polymerase; Bcl-2, B-cell lymphoma 2.