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. 2018 Jul 5;16(3):3715–3725. doi: 10.3892/ol.2018.9080

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Copyright: © Ge et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — The invasion and metastasis capacity of IHH4-M cells was higher than that of IHH4-C cells. The results of the Transwell assay in (A) IHH4-C and (B) IHH4-M cells (magnification, ×200). (E) No lung tumor formation was identified in the IHH4-C groups (magnification, ×100). (C) The number of cells able to invade through the Matrigel insert was significantly higher in IHH4-M cells, compared with IHH4-C cells. *P<0.001. (D) No significant difference was identified between the proliferation of IHH4-M and IHH4-C cells. (F) Apparent lung tumor formation was identified in the IHH4-M groups (magnification, ×100). CK19 protein expression was relatively low in the (G) IHH4-C groups, compared with higher levels in the (H) IHH4-M groups (magnification, ×200).