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. 2018 Jun 28;16(3):2789–2796. doi: 10.3892/ol.2018.9036

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Prophylactic effect of rAAV-endostatin in RCC tumor development. (A) The prophylactic immunization model. rAAV-endostatin inhibited bladder cancer occurrence and development effectively. (B) A total of 4 weeks following subcutaneous inoculation, OS-RC-2 tumors with rAAV-endostatin immunization developed 50% xenograft tumors but the controls was 100% (8/8 mice), and the (C) volume and (D) weight of tumors were all less compared with the controls (analyzed by analysis of variance). rAAV, recombinant adenovirus-associated vector; EYFP, enhanced yellow florescent protein. *P<0.05.