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. 2018 Jul 11;16(3):3509–3516. doi: 10.3892/ol.2018.9131

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Copyright: © Jia et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Autophagy inhibitor CQ promotes high expression of multiple DRs downstream of CHOP. (A) mRNA expression of CHOP in QBC939 cells following treatment with 50 µM CQ *P<0.05 vs. control. (B) Quantitative polymerase chain reaction analysis of the mRNA expression of DR genes in QBC939 cells treated with 50 µM CQ. *P<0.05 vs. control. DR, death receptor; CHOP, C/EDP homologous protein; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; FAS, Fas cell surface death receptor; TNFR2, TNF receptor 2; CQ, chloroquine; DCR1, TNF receptor superfamily member 10c; DCR2, TNF receptor superfamily member 10d. DR3, TNF receptor superfamily member 25; DR4, TNF receptor superfamily member 10a; DR5, TNF receptor superfamily member 10b.