Figure 1.

Immunohistochemical staining for TPX2 protein expression in PCa and adjacent benign tissues. (A) The whole scanned image of the tissue array (B) Statistical analyses indicated an increased immunoreactivity score in cancer tissues compared with benign tissues. (C) Enlarged image of BPH tissue indicated that TPX2 was only weakly expressed in benign tissues. Red box demonstrates the blue box at a magnification. (D) Enlarged image of PCa tissue demonstrated that TPX2 was highly abundant in the nucleus and cytoplasm of tumor cells. Red box demonstrates the blue box at a magnification. TPX2, Targeting protein for Xenopus kinesin-like protein 2; PCa, prostate cancer; BPH, benign prostatic hypertrophy. *P<0.05.