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. 2018 Jul 5;16(3):3489–3498. doi: 10.3892/ol.2018.9081

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Dual knockdown of survivin and XIAP further suppresses cell proliferation. (A) Effect of siRNA-mediated knockdown of survivin and/or XIAP on HGC-27 cell viability. (B) Proliferation of cells transfected with survivin, XIAP or survivin/XIAP siRNAs. Data are expressed as the mean ± standard error of the mean. n=3. *P<0.05, **P<0.01 vs. NC group (one-way analysis of variance with the Student-Newman-Keuls post hoc test). XIAP, X-linked inhibitor of apoptosis protein; si, small interfering RNA; NC, negative control (transfected with control nonsense siRNA); BrdU, bromodeoxyuridine.