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. 2018 Jul 11;16(3):3587–3592. doi: 10.3892/ol.2018.9121

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Copyright: © Yin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — miR-329 inhibited the viability and invasion of CRC cells. (A) Among all the colorectal normal cell line (NCM460) and the CRC cell lines (HCT116, HCT15, SW480, SW620), miR-329 showed a significant decreased expression in HCT116 and SW480. (B and C) miR-329 expression was significantly increased after transfection of miR-329 mimic in HCT116 cells and SW480 cells. (D and E) Overexpression of miR-329 in HCT116 cells significantly reduced cell invasion. (F and G) Overexpression of miR-329 in SW480 cells resulted in a significant decrease in cell viability and invasion ability. CRC, colorectal cancer. *P<0.05; **P<0.01; ***P<0.001.