Table II.

Detection performances of circular RNA reported by 10 studies.

First author	Diagnostic OR (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	Positive LR (95% CI)	Negative LR (95% CI)	(Refs.)
Li et al	7.16 (3.77–13.59)	0.81 (0.72–0.88)	0.62 (0.52–0.72)	2.16 (1.65–2.82)	0.30 (0.20–0.46)	(18)
Qin et al	9.23 (4.62–18.44)	0.81 (0.71–0.88)	0.69 (0.58–0.78)	2.57 (1.86–3.55)	0.28 (0.18–0.44)	(19)
Wang et al	6.04 (2.01–18.17)	0.68 (0.49–0.83)	0.74 (0.55–0.88)	2.63 (1.38–5.00)	0.43 (0.25–0.75)	(20)
Shang et al	45.00 (9.73–208.08)	0.83 (0.65–0.94)	0.90 (0.73–0.98)	8.33 (2.81–24.67)	0.19 (0.08–0.42)	(21)
Chen et al	6.38 (3.49–11.66)	0.72 (0.62–0.80)	0.71 (0.61–0.80)	2.50 (1.81–3.46)	0.39 (0.28–0.55)	(22)
Huang et al	4.64 (1.94–11.09)	0.85 (0.73–0.93)	0.45 (0.32–0.58)	1.55 (1.20–1.99)	0.33 (0.17–0.65)	(23)
Fu et al	5.40 (2.70–53.33)	0.45 (0.35–0.55)	0.87 (0.79–0.93)	3.43 (2.01–5.83)	0.63 (0.53–0.76)	(24)
Yin et al	12.00 (2.70–53.33)	0.80 (0.56–0.94)	0.75 (0.51–0.91)	3.20 (1.45–7.05)	0.27 (0.11–0.66)	(25)
	4.00 (0.98–16.27)	0.80 (0.56–0.94)	0.50 (0.27–0.73)	1.60 (0.98–2.61)	0.40 (0.15–1.07)
	3.50 (0.94–12.97)	0.70 (0.46–0.88)	0.60 (0.36–0.81)	1.75 (0.95–3.22)	0.50 (0.23–1.07)
Yao et al	12.33 (6.31–24.09)	0.82 (0.74–0.89)	0.73 (0.63–0.81)	3.00 (2.16–4.16)	0.24 (0.16–0.38)	(26)
Zhao et al	6.74 (3.58–12.69)	0.54 (0.44–0.63)	0.85 (0.77–0.91)	3.65 (2.28–5.84)	0.54 (0.44–0.67)	(27)

OR, odds ratio; LR, likelihood ratio; CI, confidence interval.