Table IV.
Summary of the estimates of diagnostic value, with 95% CIs.
| Category | Sensitivity | Specificity | LRP | LRN | DOR | AUC |
|---|---|---|---|---|---|---|
| Country | ||||||
| China | 0.79 (0.76–0.82) | 0.79 (0.76–0.81) | 3.7 (3.3–4.2) | 0.26 (0.23–0.30) | 14 (11–18) | 0.86 (0.82–0.89) |
| Non-China | 0.72 (0.58–0.82) | 0.88 (0.68–0.96) | 5.8 (1.9–17.7) | 0.32 (0.19–0.54) | 18 (4–87) | 0.85 (0.81–0.88) |
| Sample type | ||||||
| Serum | 0.76 (0.72–0.79) | 0.81 (0.75–0.85) | 3.9 (3.0–5.1) | 0.30 (0.25–0.35) | 13 (9–19) | 0.84 (0.81–0.87) |
| Plasma | 0.82 (0.76–0.86) | 0.78 (0.75–0.82) | 3.8 (3.2–4.4) | 0.24 (0.19–0.30) | 16 (12–22) | 0.86 (0.83–0.89) |
| ESCC only | 0.79 (0.75–0.82) | 0.79 (0.76–0.82) | 3.8 (3.3–4.4) | 0.27 (0.23–0.31) | 14 (11–18) | 0.86 (0.83–0.89) |
| Overall | 0.79 (0.76–0.82) | 0.79 (0.76–0.82) | 3.8 (3.3–4.3) | 0.27 (0.23–0.31) | 14 (11–18) | 0.86 (0.83–0.89) |
CIs, confidence intervals; LRP, likelihood ratio positive; LRN, likelihood ratio negative; DOR, diagnostic odds ratio; AUC, area under the ROC curve; ESCC, esophageal squamous cell carcinoma.