Figure 1.

Expression of PD-L1, PD-1 and CD-8 in tonsillitic tissues, normal cervix and cervical cancer were examined by IHC. The strongly stained mononuclear cells in tonsillitic tissues were identified as T lymphocytes by clinical pathologists and used as a standard to identify the lymphocytes in the cervical tissues. Expression of PD-L1, PD-1 and CD-8 in 97 samples of cervical cancer tissues and 30 normal cervix tissues were examined by IHC. The typical pictures were shown. PD-L1, PD-1 and CD-8 all had higher expression in cervical cancer. Moreover, PD-1 and CD-8 had similar expression pattern. They were strongly stained in stromal mononuclear cells around the tumor cells. The mononuclear cells were identified as tumor infiltration lymphocytes (TILs). PD-L1 mainly expressed in tumor cells.