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. 2018 Jul 5;8(15):4033–4049. doi: 10.7150/thno.24945

Figure 6.

Figure 6

Tumor distribution of Cy5.5-let-7b determined by real-time RT-PCR and plasma concentration of GDC-0449 after single injection of emulsion and micellar formulations of Cy5.5-let-7b and GDC-0449 in orthotopic pancreatic tumor-bearing NSG mice. (A) Relative let-7b levels in tumors at different time points. Results are represented as the mean ± S.D. (n=3). (B) Plasma concentration of GDC-0449. (C) Percentage of injected dose of GDC-0449. Results are represented as the mean ± S.D. (n=4).