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. 2017 Jun 7;2(2):100–110. doi: 10.1016/j.ncrna.2017.06.001

Table 2.

lncRNAs associated with heart disease and potential therapeutic targets.

lncRNAs Species Model Outcome Ref
Bvht mouse mouse embryonic stem cells cardiac fate [21]
CDR1AS human acute myocardiac infarction circulating lncRNA [132]
Chaer mouse transverse aortic constriction (TAC) regulates cardiac hypertrophy [120]
Chast mouse transverse aortic constriction (TAC) regulates cardiac hypertrophy [121]
Fendrr mouse mouse embryo cardiac lineage commitment [143]
LINC00323 human human umbilical vein Ecs, hypoxia condition angiogenesis and capilary formation [127]
LIPCAR human cardiac remodelling circulating lncRNA [131]
MIR503HG human human umbilical vein Ecs, hypoxia condition angiogenesis and capilary formation [127]
MALAT1 human human umbilical vein Ecs, hypoxia condition induces angiogenic sprouting and migration [126]
NRF mouse ischemia/reperfusion cardiomyocytes necrosis [124]
SMILR human human saphenous vein vascular smooth muscle cells smooth muscle cell proliferation [128]
SENCR human human coronary artery smooth muscle cells smooth muscle cell migration [129]
ZFAS1 human acute myocardiac infarction circulating lncRNA [132]