Skip to main content
. 2017 Jan 13;2(1):18–26. doi: 10.1016/j.ncrna.2016.12.002

Fig. 5.

Fig. 5

miR-199b regulation of post-MI cardiac remodeling involves the Notch signaling pathway. (a) Sequence alignment of human miR-199b seed region and 3′UTRs of human and mouse notch1 and jagged1. (b,c) Real-time PCR analysis of transcript abundance of (b) notch1 and (c) jagged1 in WT or miR-199b transgenic (TG) murine hearts after 4 weeks of sham or MI. (d,e) Real-time PCR analysis of transcript abundance of (b) notch1 and (c) jagged1 in murine hearts subjected to sham or MI, and treated either with antagomir-control or antagomir-199b. n = 4–6 *P<0.05 (mean ± s.e.m.).