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Influence of microRNAs on cellular sensitivity or resistance to camptothecin derivatives and to trabectedin.
| Compounds | Sensitivity | Resistance |
|---|---|---|
| Camptothecin | miR-15a [63], miR-16 [63] | miR-125b [62] |
| Irinotecan | let-7a [71], miR-451 [66], miR-519c [68] | miR-21 [67], miR-23a [69], miR-24 [73], miR-345 [72] |
| Topotecan | miR-124-5p [75] | miR-21 [74], miR-24 [73], miR-34b [75], miR-431 [75], miR-518c-AS [75] |
| Trabectedin | let-7e [78], miR-98 [78], miR-130a [78], miR-192 [78] | miR-7 [78], miR-21 [78] |
