Table 6.

Regulation of microRNAs by natural aliphatic carboxylic acids.

Compounds	Tumor suppressors (up-regulated)	Oncogenes (down-regulated)
NaB	miR-15a [112], miR-16-1 [112], miR-31 [115], miR-95 [110], miR-96 [110], miR-101 [113], miR-125a-5p [114], miR-143 [113], miR-145 [113], miR-183 [110], miR-184 [110], miR-202 [110], miR-487b [110], miR-194 [110], miR-215 [110], miR-300 [110], miR-320b [110], miR-381 [110], miR-424 [110], miR-492 [110], miR-583 [110], miR-602 [110], miR-637 [110,], miR-874 [110], miR-1908 [110]	miR-17-92 cluster [110], miR-106a-363 cluster [110], miR-106b-25 cluster [110], let-7b-3p [110], miR-7 [110], miR-34a [110], miR-106b [111], miR-135a [110], miR-196b [110], miR-221 [110], miR-222-5p [110], miR-886 [110]
TSA	miR-1 [123], miR-7 [121], miR-15a [124], [125], [126], miR-16-1 [124], [125], [126], miR-22 [123], miR-125a-5p [122], miR-129 [127], [128], miR-139 [123], miR-143 [123], miR-144 [123], miR-153 [123], miR-182-3p [127], miR-191* [123], miR-194 [123], miR-202* [123], miR-215 [123], miR-335 [123], miR-373 [124], [125], miR-375 [129], miR-449a/b [127], [131], miR-486 [123], miR-559 [123]	miR-106b-93-25 cluster [120], miR-500 [123], miR-645 [123]
TSA + antimetabolites	miR-1-1 [136], [137], miR-10b [133], miR-29b [132], miR-30b [132], miR-31 [132], miR-219-2-3p [134], miR-362-3p [135]	–
TSA + zebularine	let-7a [138], miR-26b [138]	–
n-3 PUFAs	let-7a [145], let-7d [143], miR-15b [143], miR-20b [144], miR-21 (anti-angiogenic) [145], miR-23b [145], miR-27b [145], miR-107 [143], miR-191 [143], miR-297* [147], miR-324-5p [143], miR-320b [145]	miR-21 [146], miR-143 [144], miR-467c [147], miR-1903 [147], miR-3068 [147]