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. 2018 Aug 10;9:314. doi: 10.3389/fgene.2018.00314

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Copyright © 2018 Zhao and Usdin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expansion in the female germline. (A) Distribution of allele classes in ova retrieved from 6-week-old and 10-week-old females with 155–165 repeats. Alleles that were bigger than, the same as or smaller than the maternal alleles are plotted. (B) The average number of repeats added to the progeny alleles was plotted as a function of maternal age at the birth of each litter. The data represent a total of 231 KI pups in 79 litters from 14 mothers with 145–155 repeats. Each time point represents the average of at least 18 animals.