Table 1.
Patient, tumor, and nutritional data at diagnosis for all patients and divided into patients who survived 5 years or deceased in 5 years
| Groups | All patients | 5-year survivors | 5-year non-survivors | p value |
|---|---|---|---|---|
| No. of subjects | 128 | 80 | 48 | |
| Age (years) | ||||
| Mean (SD) | 61.4 (11.2) | 58.2 (10.7) | 66.7 (10.0) | <.001 |
| Median (range) | 60 (35–87) | 57 (35–81) | 66 (51–87) | |
| Gender, no. (%) | ||||
| Male | 87 (68) | 54 (68) | 33 (69) | |
| Female | 41 (32) | 26 (33) | 15 (31) | 1.0 |
| Performance statusa | ||||
| 100 | 62 (48) | 47 (59) | 15 (31) | |
| 90 | 47 (37) | 27 (34) | 20 (42) | |
| 80 | 15 (12) | 4 (5) | 11 (23) | |
| 70 | 4 (3) | 2 (3) | 2 (4) | < .001 |
| Tumor site | ||||
| Oropharynx | 74 (58) | 49 (61) | 25 (52) | |
| Oral cavity | 41 (32) | 18 (23) | 23 (48) | |
| Unknown primary | 10 (8) | 10 (13) | 0 | |
| Hypopharynx | 2 (2) | 2 (3) | 0 | |
| Nasopharynx | 1 (1) | 1 (1) | 0 | .006 |
| T classification | ||||
| T0 | 10 (8) | 10 (13) | 0 | |
| T1 | 17 (13) | 14 (18) | 3 (6) | |
| T2 | 32 (25) | 22 (28) | 10 (21) | |
| T3 | 20 (16) | 14 (18) | 6 (13) | |
| T4 | 49 (38) | 20 (25) | 29 (60) | < .001 |
| N classification | ||||
| N0 | 32 (25) | 20 (25) | 12 (25) | |
| N1 | 34 (27) | 19 (24) | 15 (31) | |
| N2 | 49 (38) | 35 (44) | 14 (29) | |
| N3 | 13 (10) | 6 (8) | 7 (15) | 1.0 |
| Stage | ||||
| III | 33 (26) | 24 (30) | 9 (19) | |
| IV | 95 (74) | 56 (70) | 39 (81) | .23 |
| Weight lossb (%), mean (SD) | 3.15 (4.77) | 2.22 (4.04) | 4.71 (5.49) | .002 |
| Weight (kg) | 75.1 (13.8) | 77.1 (13.9) | 71.9 (13.1) | .046 |
| Height (cm) | 173.5 (8.4) | 174.0 (8.0) | 172.7 (9.0) | .59 |
| Body mass index (kg/m2) | 24.9 (3.8) | 25.3 (3.5) | 24.1 (4.1) | .13 |
| Resistance (Ω) | 512 (79) | 505 (73) | 523 (87) | .27 |
| Reactance (Ω) | 52.3 (11.0) | 53.9 (9.6) | 49.5 (12.6) | .006 |
| Fat-free mass percent (%) | 77.6 (7.4) | 77.1 (6.3) | 78.4 (8.9) | .22 |
| Fat-free mass index (kg/m2) | 19.2 (2.6) | 19.5 (2.6) | 18.7 (2.7) | .11 |
| Phase angle (°) | ||||
| Mean (SD) | 5.85 (0.98) | 6.13 (0.98) | 5.38 (0.79) | < .001 |
| Median (range) | 5.91 (4.06–8.45) | 6.22 (4.06–8.45) | 5.32 (4.08–7.95) | |
| Standardized phase angle (SD) | ||||
| Mean (SD) | − 0.013 (1.043) | 0.200 (1.059) | − 0.367 (0.921) | .002 |
| Median (range) | 0.035 (− 2.35–2.58) | 0.28 (− 2.17–2.51) | − 0.29 (− 2.35–2.58) |
aKarnofsky performance status
bUnintentional weight loss 6 months before diagnosis