Figure 11.
sQTLs Colocalize with Trait Associations.
(A) Overall summary of the colocalization of sQTLs with mQTLs and pQTLs.
(B) Pathway of degradation from arginine to agmatine. The derived conjugate Fer-Agm is further modified into N-Fer, N-methoxy-Agm. ADC, arginine decarboxylase; PHT, putrescine:hydroxycinnamoyltransferase. A cis-sQTL (rs#chr7.S_169266411) detected at GRMZM2G014295, which encodes a methyltransferase, colocalized with mQTL for the content of Fer-Agm (rs#chr7.S_169265854) and N-Fer, N-methoxy-Agm (rs#chr7.S_169265857). Transcripts named “T” stand for known transcript.
