Figure 3.

sQTL-Associated AS Effects.

(A) Categorization of sQTL-associated AS events. IR, intron retention; AA, alternative acceptor; AD, alternative donor; ES, exon skipping.

(B) The distribution of splicing ratio differences between genotypes at each sQTL.

(C) The distribution of isoform usage pattern. The left pattern indicates that sQTLs only affect the relative usage ratio of isoforms without involving major isoform switch between genotypes. The right pattern indicates that sQTLs involve major isoform switch with different major isoforms used between genotypes.