Table 1.
Baseline characteristics by hippocampal calcification presence
| Characteristic | Total, n = 1130 (100%) |
HC present, n = 381 (33.7%) | HC absent, n = 749 (66.3%) |
p value | Missing % |
|---|---|---|---|---|---|
| Age, years (median, IQR) | 68.7 (20) | 72.7 (16) | 67.2 (21) | < .01 | 0 |
| Gender (male) | 643 (56.9) | 217 (57.0) | 426 (56.9) | .98 | 0 |
| Stroke in medical history | 276 (24.4) | 114 (29.9) | 162 (21.6) | < .01 | 0.6 |
| Hypertension | 596 (52.7) | 208 (54.6) | 388 (51.8) | .35 | 0.9 |
| Diabetes mellitus | 171 (15.1) | 79 (20.7) | 92 (12.3) | < .01 | 0.4 |
| Hyperlipidaemia | 388 (35.3) | 165 (45.1) | 223 (30.5) | < .01 | 2.8 |
| Smoking | .43 | 7 | |||
| Current | 303 (28.8) | 102 (29.1) | 201 (28.7) | ||
| Former | 346 (32.9) | 123 (35.1) | 223 (31.8) | ||
| Never | 352 (38.2) | 125 (35.7) | 227 (39.5) | ||
| Obesity, BMI > 30 | 146 (20.6) | 48 (19.5) | 98 (21.1) | .61 | 37 |
| eGFR < 60 | 166 (14.6) | 54 (14.2) | 112 (15.0) | .85 | 0.7 |
| 1st degree family < 60 years with CVD history | 245 (32.8) | 77 (33.3) | 168 (32.6) | .85 | 34 |
HC hippocampal calcification, IQR interquartile range, CVD cardiovascular disease, eGFR estimated glomerular filtration rate [ml/min/1.73 m2, = 32,788 × (serum creatinine)−1.154 × (age)−0.203 × (0.742 if woman) × (1.210 if black)], BMI body mass index in kg/m2, data presented as n (%)