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. 2018 Jul 2;410(23):5859–5870. doi: 10.1007/s00216-018-1200-x

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Selectivity of the extraction systems for different lipid species delimited by time windows and analyzed in positive ESI mode. (A) LC-MS chromatogram of lipids present in plasma samples. (B) Venn diagrams of the number of extracted features present in the pooled extract in comparison with the tested extraction methods. (C) Venn diagrams of the number of extracted features in the extracts of the tested approaches when compared with each other. The type of lipids in each segment of the chromatogram is as follows: segment I, lysophospholipids (LPL) and monoglycerides (MG); segment II, phospholipids (PI, PC, PE, and PG), sphingomyelins (SM), and diglycerides (DG); and segment III, cholesterol esters (CE) and triglycerides (TG)