Table 2.
Comparison of bacterial genera significantly (Steel Dwass All Pairs, p values < 0.05) over- or underrepresented in CRC versus controls
| Phyla | Genera | CRC | Control | p values |
|---|---|---|---|---|
| Overrepresented in CRC | ||||
| Actinobacteria | f_Coriobacteriaceae | 0.002 ± 0.004 | 0.0003 ± 0.0005 | 0.0692 |
| Atopobium | 0.003 ± 0.01 | 0.0003 ± 0.001 | 0.0612 | |
| f_Coriobacteriaceae_Other | 0.05 ± 0.08 | 0.006 ± 0.01 | 0.0681 | |
| Bacteroidetes | Butyricimonas | 0.1 ± 0.4 | 0.06 ± 0.09 | 0.0333 |
| Odoribacter | 0.3 ± 0.4 | 0.03 ± 0.05 | 0.0514 | |
| Parabacteroides | 1.4 ± 1.3 | 0.1363299 ± 0.1 | 0.021 | |
| Porphyromonas | 0.5 ± 0.9 | 0.0 ± 0.0 | 0.0047 | |
| f_Rikenellaceae | 2.6 ± 4.0 | 1.0 ± 1.2 | 0.0605 | |
| Firmicutes | f_[Mogibacteriaceae] | 0.07 ± 0.06 | 0.009 ± 0.02 | 0.0199 |
| f_Christensenellaceae | 8.4 ± 11.9 | 0.07 ± 0.1 | 0.0042 | |
| Christensenella | 0.002 ± 0.002 | 0.0 ± 0.0 | 0.0119 | |
| f_Clostridiaceae | 0.2 ± 0.2 | 0.06 ± 0.07 | 0.0247 | |
| Clostridium | 0.2 ± 0.1 | 0.06 ± 0.06 | 0.0246 | |
| f_Dehalobacteriaceae | 0.007 ± 0.01 | 0.0 ± 0.0 | 0.0659 | |
| Dehalobacterium | 0.02 ± 0.01 | 0.0008 ± 0.001 | 0.0035 | |
| f_Lachnospiraceae | 3.1 ± 2.3 | 1.3 ± 1.6 | 0.0074 | |
| [Ruminococcus] | 0.3 ± 0.5 | 0.1 ± 0.2 | 0.0365 | |
| f_Lachnospiraceae_Other | 2.1 ± 1.9 | 1.8 ± 2.7 | 0.0525 | |
| Peptostreptococcus | 0.06 ± 0.1 | 0.0001 ± 0.0003 | 0.0157 | |
| f_Ruminococcaceae | 0.1 ± 0.07 | 0.03 ± 0.04 | 0.0023 | |
| Oscillospira | 1.3 ± 1.1 | 0.3 ± 0.3 | 0.0012 | |
| Ruminococcus | 0.6 ± 0.4 | 0.4 ± 0.6 | 0.021 | |
| f_Ruminococcaceae_Other | 1.3 ± 1.0 | 0.3 ± 0.5 | 0.0455 | |
| Selenomonas | 0.07 ± 0.3 | 0.0 ± 0.0 | 0.0119 | |
| f_Erysipelotrichaceae | 0.6 ± 1.5 | 0.06 ± 0.1 | 0.0514 | |
| [Eubacterium] | 0.6 ± 0.5 | 0.06 ± 0.1 | 0.0246 | |
| Holdemania | 0.01 ± 0.01 | 0.003 ± 0.005 | 0.073 | |
| Fusobacteria | Fusobacterium | 0.08 ± 0.1 | 0.0003 ± 0.0009 | 0.0348 |
| Proteobacteria | Oxalobacter | 0.03 ± 0.02 | 0.01 ± 0.02 | 0.0093 |
| f_Desulfovibrionaceae | 0.01 ± 0.01 | 0.004 ± 0.009 | 0.0341 | |
| Bilophila | 0.2 ± 0.2 | 0.04 ± 0.05 | 0.0066 | |
| Synergistetes | f_Synergistaceae_Other | 0.04 ± 0.09 | 0.0 ± 0.0 | 0.0659 |
| Verrucomicrobia | Akkermansia | 0.4 ± 0.4 | 0.01 ± 0.03 | 0.0399 |
| Overrepresented in controls | ||||
| Firmicutes | Megamonas | 0.0 ± 0.0 | 0.3 ± 1.5 | 0.0453 |
| Mitsuokella | 0.02 ± 0.08 | 0.7 ± 0.8 | 0.0529 | |
| Proteobacteria | f_Bradyrhizobiaceae | 0.0 ± 0.0 | 0.001 ± 0.002 | 0.0399 |
Numbers represent relative abundance (%) ± standard deviation