TABLE 1.
Demographic and clinical characteristics of 45 H7N9 survivors in China
| Characteristic | Valuea |
|||
|---|---|---|---|---|
| All cases (n = 45) | T1 (n = 19) | T2 (n = 33) | T3 (n = 28) | |
| Demographic features | ||||
| Males | 32/45 (71) | 14/19 (74) | 25/33 (76) | 21/28 (71) |
| Age | ||||
| Median, yr (IQR) | 50 (36–65) | 41 (32–73) | 50 (36–65) | 52 (34–65) |
| ≥60 yr | 19/45 (42) | 6/19 (32) | 14/33 (42) | 12/28 (43) |
| Influenza vaccination | 0/28 (0) | 0/12 (0) | 0/20 (0) | 0/16 (0) |
| Complications | ||||
| ARDS | 18/36 (50) | 12/19 (63) | 12/24 (50) | 9/22 (41) |
| Respiratory failure | 18/38 (47) | 9/19 (47) | 12/27 (44) | 10/24 (42) |
| Treatment and clinical course | ||||
| Hospitalization | 45/45 (100) | 18/18 (100) | 32/32 (100) | 28/28 (100) |
| Median (IQR) time, days | ||||
| Symptom onset to hospital admission | 4 (3–6) | 4 (3–6) | 4 (3–6) | 4 (3–6) |
| Hospitalization | 21 (16–29) | 25 (17–31) | 24 (15–30) | 17 (13–27) |
| ICU | ||||
| Admission | 14/36 (39) | 9/17 (53) | 12/26 (46) | 6/22 (27) |
| Median (IQR) time of stay, days | 23 (12–26) | 24 (12–27) | 24 (12–27) | 13 (7–25) |
| Oseltamivir treatment | 35/37 (95) | 16/17 (94) | 26/28 (93) | 20/22 (91) |
| Corticosteroid treatment | 23/38 (61) | 12/19 (63) | 16/27 (59) | 11/21 (52) |
| Mechanical ventilation | 12/34 (35) | 5/17 (29) | 8/25 (32) | 7/21 (33) |
| Follow-up | ||||
| Median (IQR) time after symptom onset, days | 110 (92–122) | 201 (188–237) | 375 (362–397) | |
| Serum sampling | 77/80 (96) | 19/19 (100) | 33/33 (100) | 25/28 (89) |
| PBMC sampling | 78/80 (98) | 18/19 (95) | 32/33 (97) | 28/28 (100) |
| Laboratory findings at sample collection time | ||||
| Leukopenia | 0/78 (0) | 0/19 (0) | 0/31 (0) | 0/28 (0) |
| Neutropenia | 0/78 (0) | 0/19 (0) | 0/31 (0) | 0/28 (0) |
| Lymphopenia | 0/78 (0) | 0/19 (0) | 0/31 (0) | 0/28 (0) |
| Raised creatine kinase | 0/66 (0) | 0/17 (0) | 0/28 (0) | 0/21 (0) |
| Creatine phosphokinase isoenzymes > 25 U/liter | 0/58 (0) | 0/14 (0) | 0/25 (0) | 0/19 (0) |
a
Values are numbers (percentages) unless stated otherwise.