TABLE 5.
Polymorphisms of residue 193 in H5 isolates that emerged 2004 to 2016
| Yr | Conservation (%)a |
||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| H5N1 |
H5N2 |
H5N3 |
H5N5 |
H5N6 |
H5N8 |
Total H5 |
|||||||||||||||
| Lys/Arg | Asn | n | Lys/Arg | Asn | n | Lys/Arg | Asn | n | Lys/Arg | Asn | n | Lys/Arg | Asn | n | Lys/Arg | Asn | n | Lys/Arg | Asn | n | |
| 2004 | 96.3 | 0.1 | 640 | 93.4 | 0.7 | 137 | 100 | 0 | 29 | 100 | 0 | 1 | 100 | 0 | 4 | 100 | 0 | 4 | 93.8 | 0.8 | 1,051 |
| 2006b | 100 | 0 | 4 | 83.3 | 16.7 | 6 | |||||||||||||||
| 2008 | 81.2 | 0.3 | 2,564 | 95.7 | 2.3 | 427 | 98.5 | 65 | 100 | 0 | 5 | 100 | 0 | 4 | 85.7 | 14.3 | 7 | 94.0 | 1.0 | 3,433 | |
| 2012 | 92.6 | 1.6 | 3,517 | 94.1 | 2.8 | 556 | 95.5 | 90 | 100 | 0 | 12 | 100 | 0 | 4 | 47.4 | 52.6 | 19 | 91.5 | 1.2 | 4,665 | |
| 2013c | 5.8 | 9.3 | 18 | ||||||||||||||||||
| 2014 | 82.0 | 0.3 | 3,971 | 9.8 | 86.7 | 68 | 14.0 | 86.0 | 71 | 85.9 | 4.2 | 5,381 | |||||||||
| 2016 | 86.6 | 0.6 | 4,162 | 85.6 | 12 | 667 | 95.9 | 97 | 97.4 | 0 | 39 | 5.9 | 80.5 | 118 | 11.6 | 88.4 | 86 | 88.4 | 6.9 | 5,693 | |
a
Conservation of the amino acid(s) in all isolate sequences. The statistical result was based on the number of isolate sequences deposited in the NCBI Influenza Database by the specified year.
b
First year when N193 emerged as H5N8.
c
First year when N193 emerged as H5N6.