Table 1.
Baseline characteristics of female beneficiaries by BRCA testing and time period (1997–2016) in the MarketScan database
| Characteristics | All | Ever BRCA tested | Non BRCA tested | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1997–2016 | 1997–2002 | 2003–2012 | 2013–2016 | 1997–2016 | 1997–2002 | 2003–2012 | 2013–2016 | 1997–2016 | 1997–2002 | 2003–2012 | 2013–2016 | ||
| Total N | 46,364,847 (100.0) | 3,045,858 (100.0) | 34,127,783 (100.0) | 9,191,206 (100.0) | 121,480 (100.0) | 3,709 (100.0) | 79,618 (100.0) | 38,153 (100.0) | 46,243,367 (100.0) | 3,042,149 (100.0) | 34,048,165 (100.0) | 9,153,053 (100.0) | |
| Age | Mean (SD) | 43.5 (15.9) | 47.4 (17.3) | 43.6 (15.8) | 42.1 (15.5) | 42.0 (10.8) | 38.4 (8.5) | 41.8 (10.4) | 42.7 (11.6) | 43.5 (15.9) | 47.4 (17.3) | 43.6 (15.8) | 42.0 (15.5) |
| Median (IQR) | 43.0 (31.0–54.0) | 46.0 (34.0–59.0) | 43.0 (31.0–54.0) | 41.0 (29.0–53.0) | 42.0 (34.0–50.0) | 39.0 (32.0–45.0) | 42.0 (34.0–50.0) | 42.0 (34.0–52.0) | 43.0 (31.0–54.0) | 46.0 (34.0–59.0) | 43.0 (31.0–54.0) | 41.0 (29.0–53.0) | |
| Age group | 18–34 | 15,220,699 (32.8) | 775,173 (25.5) | 11,011,382 (32.3) | 3,434,144 (37.4) | 32,714 (26.9) | 1,225 (33.0) | 21,108 (26.5) | 10,381 (27.2) | 15,187,985 (32.8) | 773,948 (25.4) | 10,990,274 (32.3) | 3,423,763 (37.4) |
| 35–49 | 14,845,205 (32.0) | 963,974 (31.6) | 11,151,037 (32.7) | 2,730,194 (29.7) | 56,934 (46.9) | 2,127 (57.3) | 38,527 (48.4) | 16,280 (42.7) | 14,788,271 (32.0) | 961,847 (31.6) | 11,112,510 (32.6) | 2,713,914 (29.7) | |
| 50–64 | 12,272,751 (26.5) | 795,550 (26.1) | 9,073,954 (26.6) | 2,403,247 (26.1) | 30,590 (25.2) | 352 (9.5) | 19,496 (24.5) | 10,742 (28.2) | 12,242,161 (26.5) | 795,198 (26.1) | 9,054,458 (26.6) | 2,392,505 (26.1) | |
| 65–74 | 2,068,107 (4.5) | 256,433 (8.4) | 1,448,898 (4.2) | 362,776 (3.9) | 1,097 (0.9) | 5 (0.1) | 428 (0.5) | 664 (1.7) | 2,067,010 (4.5) | 256,428 (8.4) | 1,448,470 (4.3) | 362,112 (4.0) | |
| 75+ | 1,958,085 (4.2) | 254,728 (8.4) | 1,442,512 (4.2) | 260,845 (2.8) | 145 (0.1) | 0 (0.0) | 59 (0.1) | 86 (0.2) | 1,957,940 (4.2) | 254,728 (8.4) | 1,442,453 (4.2) | 260,759 (2.8) | |
| Insurance | Commercial | 42,280,609 (91.2) | 2,533,752 (83.2) | 31,192,651 (91.4) | 8,554,206 (93.1) | 120,141 (98.9) | 3,701 (99.8) | 79,085 (99.3) | 37,355 (97.9) | 42,160,468 (91.2) | 2,530,051 (83.2) | 31,113,566 (91.4) | 8,516,851 (93.0) |
| Medicare | 4,073,647 (8.8) | 509,520 (16.7) | 2,928,646 (8.6) | 635,481 (6.9) | 1,319 (1.1) | 6 (0.2) | 522 (0.7) | 791 (2.1) | 4,072,328 (8.8) | 509,514 (16.7) | 2,928,124 (8.6) | 634,690 (6.9) | |
| Missing | 10,591 (0.0) | 2,586 (0.1) | 6,486 (0.0) | 1,519 (0.0) | 20 (0.0) | 2 (0.1) | 11 (0.0) | 7 (0.0) | 10,571 (0.0) | 2,584 (0.1) | 6,475 (0.0) | 1,512 (0.0) | |
| Geographic regions | Midwest | 10,439,354 (22.5) | 934,730 (30.7) | 7,846,230 (23.0) | 1,658,394 (18.0) | 21,136 (17.4) | 852 (23.0) | 14,991 (18.8) | 5,293 (13.9) | 10,418,218 (22.5) | 933,878 (30.7) | 7,831,239 (23.0) | 1,653,101 (18.1) |
| Northeast | 7,764,864 (16.7) | 397,152 (13.0) | 5,468,414 (16.0) | 1,899,298 (20.7) | 30,288 (24.9) | 454 (12.2) | 19,066 (23.9) | 10,768 (28.2) | 7,734,576 (16.7) | 396,698 (13.0) | 5,449,348 (16.0) | 1,888,530 (20.6) | |
| South | 18,041,956 (38.9) | 1,195,917 (39.3) | 13,347,681 (39.1) | 3,498,358 (38.1) | 46,321 (38.1) | 1,951 (52.6) | 29,889 (37.5) | 14,481 (38.0) | 17,995,635 (38.9) | 1,193,966 (39.2) | 13,317,792 (39.1) | 3,483,877 (38.1) | |
| West | 9,071,156 (19.6) | 442,880 (14.5) | 6,670,023 (19.5) | 1,958,253 (21.3) | 21,673 (17.8) | 446 (12.0) | 14,035 (17.6) | 7,192 (18.9) | 9,049,483 (19.6) | 442,434 (14.5) | 6,655,988 (19.5) | 1,951,061 (21.3) | |
| Missing | 1,047,517 (2.3) | 75,179 (2.5) | 795,435 (2.3) | 176,903 (1.9) | 2,062 (1.7) | 6 (0.2) | 1,637 (2.1) | 419 (1.1) | 1,045,455 (2.3) | 75,173 (2.5) | 793,798 (2.3) | 176,484 (1.9) | |
| Follow Up months | Mean (sd) | 33.6 (34.9) | 73.3 (65.8) | 34.5 (31.9) | 16.7 (11.7) | 52.3 (44.2) | 186.0 (41.1) | 60.9 (38.3) | 21.3 (12.2) | 33.5 (34.9) | 73.2 (65.7) | 34.5 (31.8) | 16.7 (11.7) |
| Median (IQR) | 24.3 (12.1–43.6) | 48.7 (18.2–121.6) | 24.3 (12.1–48.7) | 12.1 (8.1–24.3) | 36.5 (21.2–73.0) | 182.6 (161.3–220.1) | 57.8 (31.4–82.1) | 21.3 (11.1–33.4) | 24.2 (12.1–43.6) | 48.7 (18.2–120.7) | 24.3 (12.1–48.7) | 12.1 (8.1–24.3) | |
SD standard deviation, IQR interquartile range