Table 3.

Association between NRF2-regulated gene expression and arsenic concentrations in urine

Exposed	NRF2	KEAP1	HMOX1	GSTP1	NQO1	PRDX1	TRXR1
As tot. (μg/l)	0.17	0.08	0.13	0.06	0.01	0.11	0.18
As(III) (μg/l)	0.29	0.22	0.31	0.24	0.15	0.28	0.35
As(V) (μg/l)	0.16	0.15	0.16	0.14	0.06	0.27	0.18
DMA (μg/l)	0.11	0.04	0.07	0.07	− 0.01	0.13	0.12
MMA (μg/l)	0.24	− 0.01	0.01	− 0.01	− 0.01	0.13	0.19
AsB (μg/l)	0.19	0.10	0.16	0.12	0.02	0.07	0.18
As-A (μg/m3)	− 0.03	− 0.14	− 0.01	0.00	0.07	0.06	0.02
Sum iAs+MMA (μg/l)	0.28	0.13	0.22	0.15	0.09	0.25	0.31
Sum iAs (μg/l)	0.27	0.21	0.29	0.22	0.13	0.30	0.32
Sum iAs+MMA+DMA (μg/l)	0.19	0.10	0.14	0.11	0.04	0.18	0.20
Control	NRF2	KEAP1	HMOX1	GSTP1	NQO1	PRDX1	TRXR1
As tot. (μg/l)	− 0.12	− 0.19	− 0.09	− 0.14	− 0.16	− 0.16	− 0.20
As(III) (μg/l)	− 0.08	− 0.15	− 0.18	− 0.12	− 0.21	− 0.17	− 0.18
As(V) (μg/l)	0.31	0.17	0.11	0.38	− 0.18	0.34	0.09
DMA (μg/l)	− 0.10	− 0.19	− 0.08	− 0.11	− 0.18	− 0.17	− 0.17
MMA (μg/l)	− 0.12	− 0.22	− 0.25	− 0.23	− 0.15	− 0.24	− 0.18
AsB (μg/l)	− 0.13	− 0.17	− 0.06	− 0.04	− 0.10	− 0.13	− 0.19
Sum iAs+MMA (μg/l)	− 0.12	− 0.20	− 0.20	− 0.20	− 0.20	− 0.13	− 0.23
Sum iAs (μg/l)	− 0.10	− 0.19	− 0.19	− 0.18	− 0.22	− 0.12	− 0.23
Sum iAs+MMA+DMA (μg/l)	− 0.11	− 0.18	− 0.09	− 0.14	− 0.16	− 0.17	− 0.19