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. 2018 Feb 13;23(4):634–640. doi: 10.1007/s10147-018-1250-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Relationship between adverse events (AEs) and progression-free survival (PFS). a Median PFS of patients with immune-related AEs was 4.4 months, whereas that of patients without immune-related AEs was 2.1 months (p = 0.0516). b Median PFS of patients with AEs was 2.1 months, whereas that of patients without AEs was 3.4 months (p = 0.665)