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HBO therapy overcomes tumor hypoxic microenvironment. Immunohistochemistry analysis of A) pimonidazole and C) HIF‐1α. E) The expression of HIF‐1α in tumor tissue. B,D,F) Semi‐quantitative analysis of (A), (C), and (E), respectively. The scale bar is 50 µm in (A) and (C). Data as mean ± S.E. (n = 3). *P < 0.05, ***P < 0.001.
