Figure 2.

Comparison of typical N‐glycan structures from glycoproteins produced in (a) plants and (b) mammalian expression hosts. Whilst the core glycan machinery is preserved amongst eukaryotes, species‐specific modifications occur in the Golgi apparatus. Plant‐produced glycoproteins contain characteristic α‐(1,3) fucose and (β1,2) xylose residues, whereas mammalian‐derived proteins contain α(1,6)‐fucose moieties and terminal sialic acid residues. Sialylation does not occur naturally in plants.