Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 10;9:1111. doi: 10.3389/fphys.2018.01111

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Yamada, Himori, Tatebayashi, Yamada, Ashida, Imai, Akatsuka, Masuda, Kanzaki, Watanabe, Wada, Westerblad and Lanner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

ES treatment limits the increase in phosphorylation of p38 MAPK and mRNA expression of ubiquitin ligases in S-D muscles. (A) Representative Western blots illustrating the total and p-p38 MAPK (Thr180/Tyr182) of gastrocnemius muscles in control (CNT) and steroid-denervation (S-D) rats with or without ES treatment. (B) The expression levels of p-p38 MAPK was normalized to the total p38 MAPK. The expression levels of MuRF-1 (C) and atrogin-1 (D) mRNA were normalized to the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA and expressed as fold change of the mean CNT value, which was set to 1. Bars show the mean and SEM results from 5 to 6 muscles per group. ^∗P < 0.05 vs. CNT, ^#P < 0.05 vs. S-D.