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(A) Treatment history of patient 2. (B) Computed tomography images of the patient’s liver metastases (top) and lung mass (bottom) during treatment. (C) Results of tissue genotyping with SNaPshot next-generation sequencing (NGS) panel on days −29, 60, 61, and 68 and Guardant360 plasma test (mutant allele frequencies [MAFs] in parentheses) on day 57. (D) Serial circulating tumor DNA (ctDNA) droplet digital polymerase chain reaction (ddPCR) results during treatment.
