Table 2.
Clinical profiles of patients with SSc with TST higher and lower than the cutoff in ROC analysis
| Feature | Elevated TST (n = 24) | Normal TST (n = 7) | P |
|---|---|---|---|
| Male/female | 4/20 | 0/7 | 0.247 |
| Age (years) | 50.21 ± 14.01 | 37.00 ± 11.02 | 0.187 |
| Duration | 24.00 (26.40) | 56.06 ± 30.17 | 0.002* |
| DAI | 5.24 ± 2.36 | 1.84 (1.92) | 0.048* |
| mRSS | 10.00 (6.00) | 4.00 (5.00) | 0.031* |
| RP | 21 | 7 | 0.325 |
| ILD | 16 | 1 | 0.014* |
| PAH | 5 | 3 | 0.214 |
| DU | 4 | 2 | 0.483 |
| Muscular involvement | 5 | 3 | 0.214 |
| Synovitis | 10 | 2 | 0.531 |
| Scl-70(+) | 10 | 3 | 0.955 |
| CRP (mg/L) | 8.60 (10.48) | 3.52 (4.93) | 0.038* |
| ESR (mm/h) | 23.00 (16.25) | 48.71 ± 43.19 | 0.723 |
SSc systemic sclerosis, TST total skin thickness, DAI European Scleroderma Trial and Research group Disease Activity Index, RP Raynaud’s phenomenon, ILD interstitial lung disease, PAH pulmonary artery hypertension, DU digital ulcers, CRP C-reactive protein, ESR erythrocyte sedimentation rate
*P < 0.05