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. 2018 Jul 3;9(8):1340–1350. doi: 10.1039/c8md00197a

Table 2. Metabolic stability of 10h in human liver microsomes.

Code T 1/2 (min) CLint(mic) (μL min–1 mg–1) CLint(liver) (mL min–1 kg–1) Remaining (T = 60 min)
10h >145 <9.6 <8.6 81.8%
Testosterone 16.9 82.2 74.0 8.1%
Diclofenac 10.2 136.2 122.6 1.5%
Propafenone 7.7 180.9 162.8 0.5%