Table 3.
Logistic regression analysis of association of Log10(total IgE) with CVDs stratified by different categories of antigen-specific IgE.
| Classification of CVD | OR (95% CI) | p value |
|---|---|---|
| Positive food-specific IgE | ||
| Coronary heart disease | 2.916(1.305-6.517) | 0.0125 |
| Myocardial infarction | 4.006(0.255-62.988) | 0.2999 |
| Angina | 2.152(0.592-7.825) | 0.2250 |
| Stroke | 1.797(0.540-5.980) | 0.3150 |
| CVDs | 2.232(1.154-4.317) | 0.0204 |
| Positive animal-specific IgE | ||
| Coronary heart disease | 2.400(1.021-5.642) | 0.0454 |
| Myocardial infarction | 0.815(0.282-2.353) | 0.6872 |
| Angina | 2.952(0.955-9.128) | 0.0590 |
| Stroke | 0.849(0.372-1.936) | 0.6778 |
| CVDs | 1.721(0.775-3.822) | 0.1676 |
| Positive dust mite-specific IgE | ||
| Coronary heart disease | 2.574(0.793-8.358) | 0.1076 |
| Myocardial infarction | 0.433(0.067-2.809) | 0.3550 |
| Angina | 4.923(1.182-20.512) | 0.0310 |
| Stroke | 0.630(0.221-1.798) | 0.3622 |
| CVDs | 1.759(0.722-4.286) | 0.1964 |
| Positive plant-specific IgE | ||
| Coronary heart disease | 0.994(0.301-3.280) | 0.9909 |
| Myocardial infarction | 0.307(0.098-0.960) | 0.0433 |
| Angina | 2.512(0.620-10.182) | 0.1811 |
| Stroke | 0.562(0.289-1.094) | 0.0852 |
| CVDs | 0.996(0.356-2.789) | 0.9936 |
Note: Positive category-specific IgE result was defined as at least one positive antigen-specific IgE in this category. Total IgE didn't show any significant association with CVDs when mold- specific IgE was positive (see Supplement). Adjusted by age, gender, race, education level, diabetes mellitus, hypertension, family history of CVD, smoking status, alcohol status, BMI, serum TC, homocysteine and CRP levels. Abbreviations: CVD: cardiovascular disease; OR: odds ratio; CI: confidence interval.