Figure 1.

Analysis of CLCA1 expression between responders and non-responder of CCRT in a published transcriptome database composed of rectal cancers. In the clustering analysis of upregulated genes associated with chloride channel activity (GO:0005254), CLCA1 was significantly correlated with non-responders of CCRT. Tumor specimens derived from non-responder (blue lines) and responder (yellow lines) tissue specimens were marked on top of the heatmap, and expression levels of associated genes were illustrated as a series of brightness in red and green colors, respectively. Those with unaltered mRNA expression were coded as black color in the heatmap.