Table 3.
Plasma and hepatic lipid profiles in mice 1,2,3,4
| Plasma | Liver | |||||
|---|---|---|---|---|---|---|
| Triglyceride (mg/dL) | Cholesterol (mg/dL) | LDL (mg/dL) | HDL (mg/dL) | Triglyceride (mg/g) | Cholesterol (mg/g) | |
| Con (4) | 122 ± 16 | 49 ± 6 | 43 ± 5 | 81 ± 13 | 18 ± 6 | 3.2 ± 0.3 |
| HFD (4) | 163 ± 23 # | 59 ± 8 # | 54 ± 6 # | 98 ± 9 # | 35 ± 7# | 4.5 ± 0.5 # |
| Con (8)+saline | 132 ± 22 a | 47 ± 10 a | 44 ± 8 a | 73 ± 10 a | 19 ± 6 a | 3.5 ± 0.3 b |
| HFD (8)+saline | 192 ± 24 b | 73 ± 11 c | 70 ± 8 c | 109 ± 35 b | 40 ± 3 d | 4.9 ± 0.6 c |
| HFD (8)+LBNG | 160 ± 28 a | 63 ± 5 b | 62 ± 8 b | 112 ± 10 b | 34 ± 3 c | 4.0 ± 0.6 b |
| HFD (8)+MBNG | 143 ± 30 a | 54 ± 8 ab | 55 ± 11ab | 109 ± 25 b | 31 ± 7 bc | 3.8 ± 0.8 b |
| HFD (8)+HBNG | 138 ± 44 a | 57 ± 9 ab | 52 ± 7 a | 113 ± 22 b | 27 ± 5 b | 3.3 ± 0.6 a |
1 Values are means ± SD.
2 Con (4) = mice received standard control diet for 4 weeks (n=7); HFD (4) = mice received high fat diet for 4 weeks (n=7); Con (8)+saline = mice received standard control diet for 8 weeks (n=7); HFD (8)+saline (n=10), HFD (8)+LBNG (n=10), HFD (8)+MBNG (n=10), and HFD (8)+HBNG (n=10) groups = mice received high fat diet for 8 weeks and supplemented daily with 0, 0.026, 0.035, and 0.052 g BNG-1/30 g body weight at the last 4 weeks, respectively.
3 LDL = low density lipoprotein; HDL = high density lipoprotein.
4 #p < 0.05 vs Con (4) group; additionally, values in the same column with different superscripts are significantly different (p < 0.05).