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Japanese miso Kurasaigetsuusujiomiso (KU) extract enhances GRP78 expression and inhibits HAV HA11-1299 genotype IIIA strain replication in PXB cells. Western blot analysis of GRP78 and GAPDH expression levels in PXB treated with or without 0.5% KU for 24 hours (a), (b). (c) KU inhibits HAV replication in PXB. HAV RNA levels were measured by real-time RT-PCR. *p < 0.05 and **p < 0.01, compared to the untreated control (C). Data are presented as the mean ± SD of triplicate samples.
