Fig. 2.

Expression of CCKBR/p-ERK/p-P65 in ER⁺ and ER⁻BC tissues. a Expression of CCKBR, p-ERK and p-P65 in 5 paired primary BC and para-BC tissues of different subtypes detected by IHC. Case1:HER2⁻ER⁺PR⁺ Case2:HER2⁻ER⁺PR⁺ Case3:HER2⁻ER⁺PR⁺ Case4:HER2⁻ER⁻PR⁻(TNBC) Case5: HER2⁺ER⁻PR⁻ Scale bar: 50 μm. b Expression of CCKBR, p-ERK and p-P65 in 5 paired primary BC and para-BC tissues of different subtypes detected by Western blot. (c-e) Expression of CCKBR, p-ERK and p-P65 in MCF-7(ER⁺), T-47D(ER⁺) and MDA-MB-231(ER⁻) cells detected by Western blot