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Characteristics of the HPV18-VLP mAbs
| MAb | Isotypea | Epitope recognized | Inhibitory concentration (μg/ml) of mAbs against HPV-PsV infection | Inhibition ratec | |
|---|---|---|---|---|---|
| IC50 | IC90 | ||||
| 1B1 | IgG1 | Cb | 0.039 | 0.043 | 48.63% |
| 4C2 | IgG1 | C | 10.000 | 0.037 | 33.98% |
aantibody isotype, classified by indirect ELISA;
bConformational epitope, confirmed by indirect ELISA;
ctested upon competition experiment of neutralizing serum against antibody in vitro by ELISA
