Table 2.
mAb | HPV18 | Othersb | ||||
---|---|---|---|---|---|---|
Ka (Ms− 1)a | Kd (s− 1)a | KD (M)a | Ka (Ms− 1) | Kd (s− 1) | KD (M) | |
1B1 | 9.31 × 105 | 1.92 × 10− 3 | 2.06 × 10−9 | N/Ac | N/A | N/A |
4C2 | 2.38 × 106 | 1.78 × 10−2 | 7.45 × 10− 9 | N/A | N/A | N/A |
aKa is the binding constants, Kd is the dissociation constant, KD is the binding affinity;
bHPV L1-VLP of other types, including HPV16, HPV58, HPV6, HPV11, HPV31VLP, HPV33, HPV45, and HPV52;
cNot Applicable