Skip to main content
. 2018 Aug 16;19:619. doi: 10.1186/s12864-018-5003-4

Table 5.

Significant SNPsa associated with deregressed EBV for residual variance (dEBVv)

SNP Chr Position (Mb) BF MAF SNP effect Windowsb % Varc Candidate Genesd
rs133244984 3 45.30 61.24 0.32 0.00221 Chr3_46 8.67 DPYD
rs137051934 16 20.84 57.29 0.40 0.00190 Chr16_21 5.13
rs135408640 3 45.29 35.74 0.41 0.00117 Chr3_46 8.67 DPYD
rs42014753 22 51.60 33.97 0.37 0.00112 Chr22_52 1.73 UBA7, IP6K1, GMPPB, RNF123, MST1, APEH, AMT, RHOA, USP4, USP19, IMPDH2, NDUFAF3, SLC25A20, PRKAR2A, IP6K2, UQCRC1, UCN2, PFKFB4, SHISA5
rs110480161 5 22.01 33.44 0.45 0.00110 Chr5_23 2.38 BTG1
rs136349671 3 44.37 32.98 0.39 0.00106 Chr3_45 1.65 PLPPR4, PLPPR5
rs137143404 3 41.54 27.60 0.50 −0.00087 Chr3_42 1.54
rs135488380 3 45.34 23.95 0.34 0.00079 Chr3_46 8.67 DPYD
rs137135953 28 41.34 23.88 0.37 0.00074 Chr28_42 0.84 BMPR1A, ADIRF, GLUD1
rs133451489 12 4.46 23.48 0.39 −0.00072 Chr12_5 1.69
rs109757968 21 62.41 20.46 0.33 0.00065 Chr21_63 0.67 TCL1B, TCL1A, BDKRB2, BDKRB1, AK7
rs136908466 5 22.06 20.28 0.43 −0.00063 Chr5_23 2.38 BTG1
rs137014141 14 14.47 20.16 0.35 0.00062 Chr14_15 0.85

a Single nucleotide polymorphisms (SNPs) that showed a strong association with ln_σe^2 according Bayes Factor (BF > 20)

b Represented by chromosome (Chr) and physical position (in Mb) (i.e. Chr_Mb)

c Proportion of genetic variance in each 1-Mb window

d Ensembl Database UMD3.1. See the complete gene list in each window in Additional file 1