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. 2018 Aug 8;7:20. doi: 10.1186/s40035-018-0122-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Ex vivo analysis of presymptomatic spinal cord of ALS mice by Ultra-High Field MRI diffusion. a Scheme representing MRI cross- sections from different spinal cord segments (cervical, thoracic, and lumbar) used for analysis. b T2w representative MR images from individual spinal cords scans showing the white matter (WM) ROIs in the WM anterolateral funiculus (white dotted line) from each spinal cord segment (YFP vs. G93A-SOD1 mice) Scale bar = 1 mm. Abbreviations: WM: white matter. YFP: yellow fluorescent protein