Table 2.
Lesion of uncertain malignant potential (B3) on CBN with excision histology outcome for different B3 lesions and associated PPV for breast malignancy
| Category of B3 diagnosis (CNB) with excision histology (number of cases) | Final excision diagnosis | |||
|---|---|---|---|---|
| Benign | Malignant in situ no. (%) | Malignant invasive no. (%) | PPV (%) excision histology | |
| FEA (73) | 58 | 11 (15.1) | 4 (5.4) | 20,5 (15/73) |
| ADH (135) | 81 | 32 (23.7) | 22 (16.3) | 40 (54/135) |
| Papillary lesion (37) | 32 | 2 (5.4) | 3 (8.1) | 13.5 (5/37) |
| Radial scar (24) | 20 | 3 (12.5) | 1 (4.1) | 16.6 (4/24) |
| LN (30) | 30 | 0 | 0 | 0 (0/30) |
| Total (299) | 221 | 48 (16.1) | 30 (10) | 26,1 (78/299) |
FEA flat epithelial atypia, ADH atypical ductal hyperplasia, LN lobular neoplasia, CBN core needle biopsy, PPV positive predictive value