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. 2018 Aug 16;10:81. doi: 10.1186/s13195-018-0412-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Amyloid-beta (Aβ) peptide does not induce T cell cytokine secretion from peripheral blood mononuclear cells (PBMCs) of aged and young subjects. PBMCs from aged and young subjects were stimulated with Aβ42 peptide (pep) for 6 days. Bar graphs depict the level of the cytokines tumor necrosis factor (TNF)-α, interferon (IFN)-γ, interleukin (IL)-17, and IL-10 in the supernatants after 6 days as determined by specific ELISA. Results are shown as mean ± SEM of 6 different aged and 6 different young subjects. p values are based on two-tailed, parametric paired t tests with 95% confidence interval. Comparison of stimulated DCs in each group was performed against the control of the same age group. fib fibril