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. 2018 Jul 1;14(10):1186–1195. doi: 10.7150/ijbs.24898

Figure 2.

Figure 2

Changes in serum transaminase levels, liver histology, cell apoptosis, and apoptosis-related proteins in mice subjected to y IRI with or without IPC and TIM4 blocking. (A) Serum alanine transaminase (ALT) and aspartate transaminase (AST) levels determined using enzyme-linked immunosorbent assay. (*P < 0.05, ***P < 0.001) (B-C) Liver histology examined using hematoxylin and eosin (HE) staining, and cell apoptosis examined using TUNEL assay (magnification, ×400; *P < 0.05 vs. IRI; n = 3 for each experiment). (D) Apoptosis-related protein expression determined using western blot analysis (*P < 0.05, ***P < 0.001 vs. IRI; n = 3 for each experiment).