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. 2018 Jul 27;14(10):1389–1398. doi: 10.7150/ijbs.24739

Fig 2.

Fig 2

Peptide R1-P2 inhibits the activity of A549 and NCI-H460 cells in vitro. (A) Peptide R1-P2 inhibited phosphorylation of FGFR1 and ERK1/2 induced by FGF2 (n = 3). (B) Peptide R1-P2 inhibited the vabilility of A549 and NCI-H460 cells measured by MTT assay (n = 3). (C) Peptide R1-P2 induced apoptosis in A549 and NCI-H460 cells measured by TUNEL (n = 3). (D) Peptide R1-P2 remarkably inhibited A549 and NCI-H460 cells migration (n = 3). (E) Peptide R1-P2 strongly suppressed A549 and NCI-H460 cells invasion measured by transwell assay (n = 3). Bar = 100 μm, the error bars indicate the ± SD from three separate experiments, *P < 0.05, **P < 0.01, ***P < 0.001, versus control.