Table 1. Bivariate analysis of sociodemographic, clinical, and medication data in AKI and non-AKI-groups of patients admitted at a teaching hospital ICU.
| Variables | Total (n = 122) | Non-AKI group (n = 93) | AKI group (n = 29) | p-valuea,b |
|---|---|---|---|---|
| Sociodemographic data | ||||
| Female sex, n (%) | 51 (41.8) | 39 (41.9) | 12 (41.4) | 0.96a |
| Age, median (IQ) | 46.0 (29.0–69.0) | 41 (28.0–63.0) | 62.0 (46.0–76.0) | 0.01b |
| Race, n (%) | ||||
| White | 95 (77.9) | 76 (81.7) | 19 (65.5) | 0.07a |
| Non-white | 27 (22.1) | 17 (18.3) | 10 (34.5) | |
| History of ethanol use, n (%) | 45 (37.8) | 34 (37.8) | 11 (37.9) | 0.99a |
| Smoking status, n (%) | 35 (29.4) | 26 (28.9) | 9 (31.0) | 0.83a |
| Clinical data | ||||
| APACHE II Score at admission ICU, (IQ) | 21.4 (15.0–27.0) | 20.1 (14.0–25.0) | 25.6 (20.0–31.0) | <0.01b |
| Comorbidities, n (%) | ||||
| 0 | 51 (41.8) | 44 (47.3) | 7 (24.1) | 0.05a |
| 1–2 | 45 (36.9) | 33 (35.5) | 12 (41.4) | |
| >2 | 26 (21.3) | 16 (17.2) | 10 (34.5) | |
| Sedation, n (%) | 67 (54.9) | 45 (48.4) | 22 (75.9) | 0.01a |
| Trauma, n (%) | 47 (38.5) | 40 (43.0) | 7 (24.1) | 0.07a |
| Mechanical ventilation, n (%) | 82 (67.2) | 58 (62.4) | 24 (82.8) | 0.04a |
| Infection, n (%) | 49 (40.2) | 29 (31.2) | 20 (69.0) | <0.001a |
| Sepsis, n (%) | 20 (16.4) | 12 (12.9) | 8 (27.6) | 0.06a |
| Length of ICU stayc (days), n (%) | ||||
| Up to 5 | 56 (45.9) | 50 (53.8) | 6 (20.7) | 0.01a |
| From 6 to15 | 36 (29.5) | 23 (24.7) | 13 (44.8) | |
| More than 15 | 30 (24.6) | 20 (21.5) | 10 (34.5) | |
| ICU Discharge, n (%) | ||||
| Discharge | 111 (91.0) | 89 (95.7) | 22 (75.9) | <0.01a |
| Death | 11 (9.0) | 4 (4.3) | 7 (24.1) | |
| Medications | ||||
| Number of drugs in general, median (IQ) | 20.0 (15.0–27.0) | 19.0 (14.0–26.0) | 25.0 (20.0–35.0) | <0.001b |
| Number of potentially nephrotoxic drugs, n (%) | ||||
| 0–6 | 34 (27.9) | 30 (32.3) | 4 (13.8) | 0.06a |
| 7–11 | 55 (45.1) | 42 (45.2) | 13 (44.8) | |
| >11 | 33 (27.1) | 21 (22.6) | 12 (41.4) | |
| Number of vasoactive drugs, n (%) | ||||
| 0 | 39 (32.0) | 35 (37.6) | 4 (13.8) | <0.01a |
| 1–2 | 75 (61.5) | 55 (59.1) | 20 (69.0) | |
| >2 | 8 (6.5) | 3 (3.2) | 5 (17.2) | |
Notes.
Abbreviations
- AKI
- acute kidney injury
- ICU
- intensive care unit
- IQ
- interquartile range
- APACHE II
- Acute Physiology and Chronic Health Evaluation II
- ICU
- intensive care unit
a
χ2 de Pearson.
b
Mann-Whitney.
c
Length of hospital stay prior to ICU admission was not included in this analysis.