Table 3. Frequency of use of potentially nephrotoxic drugs in the ICU patients studied at a teaching hospital (n = 122).
| Potentially nephrotoxic drugs | Frequencya, n (%) | Potentially nephrotoxic drugs | Frequencya, n (%) |
|---|---|---|---|
| Fentanyl | 86 (70.5) | Propofol | 15 (12.3) |
| Morphine | 79 (64.8) | Dobutamine | 14 (11,5) |
| Omeprazole | 78 (63.9) | Amikacin | 13 (10.7) |
| Norepinephrine | 73 (59.8) | Amiodarone | 12 (9.8) |
| Magnesium sulfate | 54 (44.3) | Carvedilol | 12 (9.8) |
| Furosemide | 46 (37.7) | Spironolactone | 12 (9.8) |
| Vancomycin | 37 (30.3) | Amoxicillin + clavulanic acid | 11 (9.0) |
| Diazepam | 35 (28.7) | Ciprofloxacin | 11 (9.0) |
| Simvastatin | 33 (27.1) | Valproic acid | 10 (8.2) |
| Metronidazole | 32 (26.2) | Clopidogrel | 10 (8.2) |
| Ceftriaxone | 31 (25.4) | Non-ionic contrast media | 10 (8.2) |
| Meropenem | 31 (25.4) | Hydralazine | 10 (8.2) |
| Polymyxin | 31 (25.4) | Clarithromycin | 9 (7.4) |
| Clonazepam | 27 (22.1) | Clonidine | 9 (7.4) |
| Phenytoin | 27 (22,1) | Gentamicin | 9 (7.4) |
| Captopril | 25 (20.5) | Calcium gluconate | 9 (7.4) |
| Amlodipine | 24 (19.7) | Phenobarbital | 8 (6.6) |
| Risperidone | 19 (15.6) | Clindamycin | 7 (5.8) |
| Losartan | 17 (13.9) | Epinephrine | 7 (5.8) |
| Sodium nitroprusside | 17 (13.9) | Hydrochlorotiazide | 7 (5.7) |
| Acetaminophen | 17 (13.9) | Oxacillin | 7 (5.7) |
| Piperacillin + tazobactam | 17 (13.9) | Atropine | 6 (4.9) |
| Tramadol | 17 (13.9) | Cefepime | 6 (4.9) |
| Cefazolin | 15 (12.3) |
Notes.
a
Potentially nephrotoxic drugs with frequency of use <5 patients were not shown in this table.
b
Iohexol or iopamidol or ioversol or iobitriol.