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. 2018 Aug 14;10:2573–2580. doi: 10.2147/CMAR.S173193

Table 3.

Results of subgroup analyses for effects of ESR1 mutation on PFS

ESR1 mutation ESR1 mutation numbers df Model HR (95% CI) Test for heterogeneity (I2)
D538G vs WT ESR1 121 2 Fixed 1.50 (1.18–1.91) 0.0%
Y537S vs WT ESR1 61 2 Random 1.65 (0.87–1.73) 83.7%

Abbreviations: df, degrees of freedom; HR, hazard ratio; PFS, progression-free survival; WT, wild type.