Table 1.
Patient demographics and baseline characteristics
| Characteristic | Overall (N = 158) | No Infections (N = 120) | Infections (N = 38) |
|---|---|---|---|
| Age (year) | 42 ± 16 | 42 ± 16 | 42 ± 16 |
| Sex (m/f) | 51/107 | 37/83 | 14/24 |
| Hemoglobin value (mg/dL) at t = 0 | 123.2 ± 28.6 | 122.1 ± 30.8 | 126.8 ± 20.1 |
| Leucocyte count (× 109/L) at t = 0 | 7.7 ± 3.4 | 7.2 ± 3.2 | 9.1 ± 3.6* |
| Platelet count (× 109/L) at t = 0 | 13.4 ± 12.2 | 13.8 ± 12.8 | 11.8 ± 10.4 |
| Hemoglobin value (mg/dL) at t = 1 month | 125.5 ± 32.2 | 124.0 ± 23.9 | 130.4 ± 50.3 |
| Leucocyte count (× 109/L) at t = 1 month | 11.0 ± 7.9 | 11.2 ± 7.8 | 10.5 ± 8.2 |
| Platelet count (× 109/L) at t = 1 month | 87.7 ± 78.7 | 107.4 ± 79.7 | 25.4 ± 24.3* |
| Bleeding score | 3.9 ± 3.4 | 3.8 ± 3.5 | 4.1 ± 3,2 |
| Duration hospital stay (days) | 10.9 ± 6.5 | 9.8 ± 5.2 | 14.0 ± 8.7* |
| Treatment (dexamethasone/prednisone) | 118/40 | 87/33 | 31/7 |
| Antibodies | |||
| None | 46 | 35 | 11 |
| GPIb-IX | 13 | 11 | 2 |
| GPIIbIIIa | 15 | 7 | 8 |
| Both | 18 | 16 | 2 |
| Unknown | 66 | 51 | 15 |
| Type of infection | |||
| Viral | 11 | ||
| Bacterial | 27 | ||
| Time of infection (day) | 5.7 ± 5.1 | ||
| Platelet transfusion | |||
| Number of patients transfused | 91 (57.6%) | 62 (51.7%) | 29 (76.3%) |
| Total amount of units | 150 | 91 | 59 |
| Median amount of units | 1 | 1 | 1 |
| Mean | 1.0 | 0.8 | 1.6* |
Mean values for age, platelet count, leucocyte count, hemoglobin values, bleeding score, hospital stay, and time of infection ± standard deviations are shown. Bleeding score was calculated by adding the points relevant to various clinical bleeding signs as described by Wei et al. [11]
*p < 0.01